SKU: 47762032449

NRF2 Protein, Human

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Description

NRF2 Protein, HumanProduct Specification Species Human Synonyms Nuclear factor erythroid 2 related factor 2,erythroid derived 2 HEBP1 like 2 Accession Q16236 Amino Acid Sequence Met1 Asn605 Expression System PichiaPastoris Molecular Weight 70. 0 kDa Purity 90% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, pH 7. 4 or 20 mM PB, 6% Trehalose, pH 7. 0. Reconstitution It is not recommended to

Product Specification


Species Human
Synonyms Nuclear factor erythroid 2-related factor 2,erythroid derived 2 HEBP1 like 2
Accession Q16236
Amino Acid Sequence

Met1-Asn605

Expression System PichiaPastoris
Molecular Weight

70.0 kDa

Purity >90% by SDS-PAGE
Endotoxin <1EU/μg
Conjugation Unconjugated
Tag His Tag
Physical Appearance Lyophilized Powder
Storage Buffer

PBS, pH 7.4 or 20 mM PB, 6% Trehalose, pH 7.0.

Reconstitution

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

Stability & Storage

Stored at -20°C for 2 years. 

After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). 

It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Background

Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.

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SKU: 47762032449

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4.1 ★★★★★
Based on 12 reviews
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E
Verified Purchase
Elizabeth from Houston
Carnegie, US
★★★★★ 5
Helps with redness and softens skin
I have sensitive, mild rosacea skin. Had a facial recently and the aesthetician suggested I get a serum to help with moisturizer as I am almost 40. I’ve tried a lot of serums and either they are sticky and not really hydrating or break my skin out in a rash. This serum is amazing. Helps calm the redness in my cheeks and my skin is moisturized and soft all day. It feels a little sticky at first but it goes away. I apply in this order OSEA sea mineral mist toner to prep the skin, this serum and top off with Chanel La Solution 10 for sensitive skin.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on December 27, 2025
C
Verified Purchase
carolyn
Birmingham, US
★★★★★ 5
Sensitive skin
Such a good product. I use after micro needling when skin is sensitive. Also a great product to use as a barrier serum when starting tretinoin cream.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 24, 2026
L
Verified Purchase
Lindsay
Pawtucket, US
★★★★★ 5
Saved my skin during an eczema flare up
This saved my skin! I had an eczema flare on my face, and my usual products weren’t working. A friend recommended the Avene brand and within 3 days of using this rescue barrier serum, my flare was almost completely gone! This saved my face!
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Reviewed in the United States on April 11, 2026
B
Verified Purchase
B Helton
Natrona Heights, US
★★★★★ 1
PLEASE REVIEW — FORMULA CHANGED!!!
I wish I would’ve posted a review PRIOR to the formula changing but just know that I LOVED this serum. I’ve struggled with hormonal acne (PCOS) and eczema for as long as I can remember. Finally, last summer my dermatologist put me on (3) different RX including Spironolactone and Accutane. I was so tired so I stopped everything except for CeraVe cleanser, retinol (Tretinoin) and CeraVe healing ointment. My made up skin routine was working until I used too much Tretinoin and burned my face. I had read great reviews about this product so I thought, I might as well try it — and IT WORKED! I’ve been using this product for almost a year and I loved it. However, 3 weeks ago when I ordered it, I noticed the bottle had a green tint. I could tell after one use that the feel of the serum was different, more watery, not as thick as it used to be. The smell was also different. Still, I kept using it for nearly 2 weeks and I experienced 2 breakouts! Sure enough, I stopped the product and within a few days, my skin was back to normal. I am very upset because as someone who has extremely sensitive skin, this worked but unfortunately, the new formula isn’t for me.
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Reviewed in the United States on May 14, 2026
H
Verified Purchase
HanTurn
New York, US
★★★★★ 5
Must Have Beauty Product
This one of my favorite and must have beauty products. Works so quickly for chapped lips and just keeping my lips soft every day. The formula isn’t sticky at all and you can really feel how hydrating and nourishing it is
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on April 11, 2026

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