SKU: 53012023110

FITC Mouse Anti-Human CD44v6 Antibody (S-945-76)

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Description

FITC Mouse Anti-Human CD44v6 Antibody (S-945-76)Product Specification Host Mouse Antigen CD44v6 Immunogen Recombinant Protein Location Cell membrane Accession NP_001001391. 1 Clone Number S 945 76 Antibody Type Mouse mAb Isotype IgG1,k Application FCM Reactivity Hu Purification Protein G Concentration 0. 2 mg ml Conjugation FITC Physical Appearance Liquid Storage Buffer PBS, 1% BSA, 0. 3% Proclin 300 Stability & Storage 12 months from date of receipt reconstitution, 2 to 8 C as supplied Dilution

Product Specification


Host Mouse
Antigen CD44v6
Immunogen Recombinant Protein
Location Cell membrane
Accession NP_001001391.1
Clone Number S-945-76
Antibody Type Mouse mAb
Isotype IgG1,k
Application FCM
Reactivity Hu
Purification Protein G
Concentration 0.2 mg/ml
Conjugation FITC
Physical Appearance Liquid
Storage Buffer

PBS, 1% BSA, 0.3% Proclin 300
Stability & Storage

12 months from date of receipt / reconstitution, 2 to 8 °C as supplied

Dilution


application dilution species
FCM 5μl per million cells in 100μl volume Hu

Background

CD44 is a polymorphic integral membrane protein, which binds to hyaluronic acid (HA), and contributes to cell-matrix adhesion, cell proliferation, migration, and tumor metastasis. When the CD44 is transcribed, its pre-messenger RNA can be received alternative splicing and maturated into mRNAs that encode various CD44 isoforms. The mRNA assembles with ten standard exons and the sixth variant exon encodes CD44v6, which plays critical roles in cell proliferation, migration, survival, and angiogenesis. Functionally, CD44v6 can interact with HA via the standard exons-encoded region. Furthermore, the v6-encoded region functions as a co-receptor of various receptors for epidermal growth factor, hepatocyte growth factor, C-X-C motif chemokine 12, and osteopontin. Therefore, the receptor tyrosine kinase or G protein-coupled receptor signaling pathways are potentiated in the presence of CD44v6. These functions are essential for homeostasis or regeneration in normal tissues. Importantly, CD44v6 overexpression plays a critical role in CRC progression. For instance, CD44v6 is involved in colorectal carcinoma invasiveness, colonization, and metastasis. Therefore, CD44v6 is a promising target for cancer diagnosis and therapy.

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SKU: 53012023110

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4.1 ★★★★★
Based on 17 reviews
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Product Reviews
A
Verified Purchase
Autumn
Alexandria, US
★★★★★ 4
Good option
Color: White, Size: Body(Pack of 1)
I’ve been using the ACCURATEX Full Body Pillow for Adults – Hybrid Shredded Memory Foam for a few weeks now, and overall I’m really happy with it. The blend of shredded memory foam gives it a firm, supportive feel, but what I love most is that you can adjust the filling to get the exact firmness you want. Whether you prefer something more structured or slightly softer, it’s easy to customize by adding or removing foam. Comfort-wise, it’s definitely a step up from standard body pillows. It keeps its shape throughout the night and offers great support for side sleeping. That said, it is a bit firmer out of the box than I expected, which is why I’m giving it 4 stars instead of 5. If you’re looking for a body pillow that won’t go flat and lets you tweak the feel to your liking, this one is a solid choice.
WAS THIS REVIEW HELPFUL?YesReportShare
Reviewed in the United States on November 14, 2025
B
Verified Purchase
Brittany
Lexington, US
★★★★★ 5
Favorite pillow!!
Color: White, Size: Body(Pack of 1)
I honestly wasn’t expecting to love this pillow as much as I do. Buying pillows online always feels risky because you can’t actually feel them beforehand, but this ended up being one of the best blind buys I’ve made on Amazon. The quality is genuinely shocking for the price. It feels way more expensive than it is. It’s insanely comfortable, supportive without feeling stiff, and just has that “perfect” cozy feel. I have neck problems, so I’m really picky about pillows, and this one somehow manages to be the perfect balance. It’s supportive without being stiff or overstuffed, but also not too flat where your neck feels unsupported. It has that perfect “sink in but still supportive” feel that’s hard to find. I loved the body pillow version so much that less than a week later I’m already ordering the regular pillow version too. Easily 5 stars from me!!
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Reviewed in the United States on May 19, 2026
Y
Verified Purchase
youngryand
Port Orchard, US
★★★★★ 5
Probably going to replace all the pillows in the house with these
Color: White, Size: King (Pack of 2)
These pillows are just about perfect. They have to be the best pillow for the money out there at least. I didn't even know that this kind of pillow existed but was asking Google Gemini what kind of pillow would best suit my list of needs and this is what we came up with. - High loft for comfortable side sleeping, but can be reduced by removing foam to be less high - Gives initially, but stays at that new same thickness throughout the night b/c it's memory foam chunks - Doesn't feel lumpy because it has the 1cm outer pillow layer that covers the memory foam pieces I'm 6/3" 210lbs and after a couple nights of adjusting I found that removing about 1 gallon ziploc of foam chunks from each pillow was about perfect. I saved the foam in ziplocs in case I change my mind. They come REALLY loaded at first so should fit literally anyone with some adjusting. It was definitely too big the first two nights until I got it just right.
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Reviewed in the United States on June 5, 2026
H
Verified Purchase
H Connelly
Carnegie, US
★★★★★ 3
Hard As Rock When Cold
Color: White, Size: Standard (Pack of 2)
These are good pillows except they get hard as a rock when the temps go below 65F and take 10-20 minutes to warm up at bedtime. Not ideal where the winters are colder or for someone with cervical spine issues.
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Reviewed in the United States on March 26, 2026
S
Verified Purchase
Shea
Dallas, US
★★★★★ 5
LUXURIOUS, just like it says
Color: White, Size: Queen (Pack of 2)
I used My Pillows for years which needed constant fluffing throughout the night until they just became useless. Since they became useless, I would always wake in the middle of the night with terrible headaches and my head would be sore all over, throbbing like a boil. I couldn’t stand anything to touch my any part of my head while these headaches occurred. One night almost a week ago I was awake in pain and couldn’t sleep. I started googling for a solution, a pillow that would support a human head, basically a bowling ball. After several products which kept sending me to Amazon, I stumbled upon this pillow. I read all of the reviews. Many compared it to a “luxurious hotel pillow”. So I waited and got them within less than 48 hours. It was a thin box so I wasn’t expecting much. They were vacuum sealed, I opened them and allowed about an hour for them to fully expand. They were comprised of memory foam and down alternative like “luxurious hotel pillows”. They were heavy too. I tried to fluff it for maximum feel. It was extremely firm and I wasn’t able to actually fluff or reform it in any manner really. I could feel the down alternative filling surrounding this semi hard center ( the memory foam I guess) and I fluffed as much as possible. I had difficulty getting it into my pillow case, which was fine to me. It just made me anticipate this perfect looking pillow. I had been suffering with these headaches due to inferior pillows, I couldn’t wait. I laid down and put my bowling ball head on it! It completely supported my head. I normally like my pillow to conform around my neck and shoulders to allow a straight alignment with my head. My head was slightly up, but hey this felt great!!! I could feel the down alternative filler cushioning my head with the firm memory foam in the middle. I could not wait to try it that night. Night comes and I’m excited to see if I can sleep through the night finally without waking with those terrible headaches. I slept almost all through the night except for going to the bathroom once!! And my head wasn’t hurting nor did it feel like a boil!! I was ecstatic to say the least. I know there are people just like me searching for relief. If you can tolerate a firm pillow you can’t go wrong with these pillows. You get two for a great price! I just wish I hadn’t wasted hundreds on My Pillows for all my bedrooms a few months ago. I will be replacing all the pillows in my home with these WONDERFUL pillows!!!
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Reviewed in the United States on March 13, 2025

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